Familial meconium ileus not associated with cystic fibrosis.

With rare exceptions, patients with meconium ileus have cystic fibrosis of the 
pancreas with pancreatic achylia, elevated salt content of sweat, and characteristic 
pulmonary manifestations. We wish to report the occurrence of meconium ileus 
in two full-term siblings with normal pancreatic function and no evidence 
of cystic fibrosis by history of physical findings, and with normal 
sweat electrolytes. To our knowledge this is the first report of 
familial meconium ileus without associated cystic fibrosis of the pancreas or 
pancreatic insufficiency. 