Effect of sera from cystic fibrosis homozygotes and heterozygotes on glucose metabolism in Vero cells.

The effect on intracellular production of carbon dioxide from glucose of sera 
from cystic fibrosis (C.F.) homozygotes and heterozygotes was determined in an 
established cell line (Vero cell) by a double-blind assay. CO2 production 
was reduced when cells were incubated with an ammonium-sulphate-precipitated fraction of 
sera from C.F. homozygotes and heterozygotes but not by a similar 
fraction from sera of healthy donors. 