The occurrence of cystic fibrosis and celiac sprue within a single sibship.

A family is presented in which celiac sprue and cystic fibrosis occurred 
within the same sibship. A cousin of the index case was 
also discovered to have celiac sprue. The genetics and incidence of 
both conditions is reviewed. It is estimated that the likelihood of 
this association occurring on the basis of chance in this family 
is 1 in 50,000. 