Iatrogenic hyperuricemia in children with cystic fibrosis.

We report the frequent presence of hyperuricemia in a group of children 
with cystic fibrosis who were known to be consuming large dosages 
of pancreatic extract as part of their therapy. Hyperuricemia was more 
common in older patients who had been treated for a longer 
period of time. Clarification of the role of renal function and 
other factors in the production of hyperuricemia awaits a careful study 
of the relationship of purine load to urate excretion at various 
ages in these patients. 