Sweat testing for cystic fibrosis. Diagnostic screening with a combination chloride ion-selective electrode.

Screening of sweat chloride in newborn infants with the Orion Skin Chloride 
Measuring System and incorporating some procedural innovations is described. The results 
indicate that while diagnostic screening for cystic fibrosis can be readily 
undertaken, the test with the chloride ion-selective electrode is best left 
at least to the second day of life or later because 
of insufficient sweating in very young babies. Measurements on 2 babies 
with cystic fibrosis are also discussed. 