Cystic fibrosis presenting with the meconium plug syndrome.

The meconium plug syndrome (MPS) is a common cause of low intestinal 
obstruction in newborn infants. Usually, it is benign and not associated 
with other intestinal dysfunction. We describe the cases of three infants 
in whom there was intestinal obstruction consistent with the MPS and 
in which cystic fibrosis (CF) was later documented. We suggest that 
there is an association between the MPS and CF, and that 
the condition of all infants with the MPS be evaluated for 
the possibility of both Hirschsprung's disease and CF. 