Intracisternal inclusion bodies induced in animals: their transformation and significance.

Intracisternal granules (Palade, 1956) or inclusion bodies occurring within the cisternae of 
the rough-surfaced endoplasmic reticulum have been observed not only in normal 
conditions, but also in some experimental conditions. In this paper, such 
intracisternal inclusion bodies were induced or found in a variety of 
animals following chemical administrations, artificial hibernation and cold exposure, and also 
with cystic fibrosis. These inclusion bodies are tentatively classified into 6 
types based upon their morphological aspects. The formation, fate and significance 
of these bodies are also discussed. 