Arginine esterase and lysosomal hydrolases in liver from cystic fibrosis subjects.

The total activity and isoelectric focusing patterns of arginine esterase, cathepsin B1, 
and several lysosomal hydrolases were normal in liver from two patients 
with cystic fibrosis. No abnormalities were observed in values for pH 
optimum, Km, and Vmax for arginine esterase and cathepsin B1 in 
liver from cystic fibrosis patients compared to those values for liver 
from the control subject. Soybean trypsin inhibitor at concentrations up to 
100 microgram/ml had no effect on liver arginine esterase or cathepsin 
B1. 