Pseudomonas aeruginosa infection in cystic fibrosis. Diagnostic and prognostic significance of pseudomonas aeruginosa precipitins determined by means of crossed immunoelectrophoresis. A survey.

The purpose of the first part of the present work is to 
review the literature concerning the lower respiratory tract infections and the 
antimicrobial resistance mechanisms in cystic fibrosis patients. The second part of 
the work deals with the most important therapeutical problem in cystic 
fibrosis today, viz. the Pseudomonas aeruginosa lung infection. A survey is 
made of the investigations of the present author and his colleagues 
into the immune response against Pseudomonas aeruginosa infection and the literature 
concerning these subjects. Furthermore, the possible mechanisms of tissue damage in 
the respiratory tract of cystic fibrosis patients during these infections are 
discussed. 