Polyamine metabolism in cystic fibrosis.

Increased blood levels of spermidine and an increased spermidine/spermine ratio is documented 
in 31 patients with cystic fibrosis (CF). Some 29 percent of 
CF patients overlap with the control group. An abnormality of urinary 
free polyamines or their metabolic derivatives related to electrolyte transport, serum 
ciliostatic factors, and the autonomic nervous system are elaborated upon. 