Recent advances in research on cystic fibrosis.

Advances have been made in two areas of cystic fibrosis research at 
the University of Missouri School of Medicine. First, investigations have improved 
understanding of the normal mechanisms that underline the production of exocrine 
secretions. The second involves recent observations relating to important efforts to 
develop methods for heterozygote detection. The author concludes that efforts should 
be made to shift emphasis in research from qualitative bioassays to 
more reliable detection systems. 