Comparative trial of pancrex V forte and nutrizym in treatment of malabsorption in cystic fibrosis.

A cross-over trial of pancreatic enzyme replacement therapy has been conducted on 
12 children with cystic fibrosis using Pancrex V forte and Nutrizym 
tablets in equivalent dosage. No differences were found in the effectiveness 
of these products as measured by stool volume, number of bowel 
actions, faecal fat excretion, and urine urea excretion. Neither product eliminated 
the steatorrhoea. Though there was no laboratory evidence to support their 
choice nine patients expressed a preference for Nutrizym at the conclusion 
of the trial. This preference was based partly on the smaller 
number of tablets which are required. 