Cystic fibrosis in 3 Pakistani children.

For Caucasians of European origin, cystic fibrosis (CF) remains the commonest recognized 
autosomal recessive disorder, but it appears to be a rarity among 
the coloured races. For a time, records may have suggested an 
association between CF and whiteness; in recent years, however, instance of 
CF children have been described whose racial origins are Negroid, Mongoloid, 
and non-European Caucasoid. The present case reports concern 3 Pakistani children 
born in Birmingham, in whom Cf has been confirmed. 2 of 
the 3 (Cases 1 and 2) were brother and sister. The 
present incidence of this disease among Asian immigrants in the West 
Midlands is approximately 1:10,000. 