Clinico-pathological evaluation of 37 cases of cystic fibrosis of the pancreas in infancy at necropsy.

The clinical and morphological findings of 37 cases of cystic fibrosis of 
the pancreas from 525 full, but non-consecutive necropsies are presented. All 
of these 37 cases were diagnosed at post-mortem examination. The autopsy 
incidence was 7% and none of the cases was beyond two 
years of age. Morphological findings revealed varying severities in organ involvement 
in all cases, with absence of fibrosis of the pancreas in 
some. In only two cases histopathological changes seemed to be confined 
to the pancreas. This study suggests that cystic fibrosis plays a 
considerable role in infant deaths in our country and in most 
if not all cases the diagnosis must necessarily be based on 
postmortem studies. 