Chronic suppurative lung disease in sisters mimicking cystic fibrosis.

Two sisters are described with fatal chronic obstructive lung disease of unknown 
origin. The lung condition was clinically and histologically indistinguishable from cystic 
fibrosis and the salivary glands showed pathological changes expected in cystic 
fibrosis. Neither child had abnormal sweat electrolytes, they had no bowel 
symptoms, and the pancreas was normal at necropsy. 