Letter: Serum alpha-fetoprotein in cystic fibrosis.

Professor R. K. Chandra and others reported significantly increased levels of alpha-fetoprotein 
(AFP) in the serum of patients with cystic fibrosis (CF), in 
the parents of the patients, and in some of their siblings 
in Newfoundland, Canada. The serum AFP levels in our 38 patients 
with CF were not different from those in healthy adults. In 
our opinion, genetic differences cannot explain the different results concerning the 
serum AFP levels in patients with CF. 