Mucociliary clearance.

Mucociliary clearance data obtained by our group in relatively healthy cystic fibrosis 
subjects was not affected by cough. The majority of subjects mentioned 
in the original article did not cough during the study and 
indeed were chosen because they were relatively healthy at the time. 
It was possible to study them over fairly long periods without 
interference from cough and thus the relatively normal clearance times demonstrated 
were presumably due to mucociliary transport. Reference was made to nasal 
mucociliary clearance studies in patients with cystic fibrosis and normal subjects 
which indicated that clearance was similar in both groups until mild 
inflammation of the nasal mucosa was produced. We would like to 
point out that the work was performed in our Laboratory, since 
no reference was given in the discussion. 