Nonoperative treatment of meconium ileus equivalent.

Intraluminal bowel obstruction secondary to inspissated feces is a known complication of 
cystic fibrosis. When seen in the older child, it is termed 
"meconium ileus equivalent." We studied a case in which nonsurgical resolution 
of the obstruction was obtained with N- acetylcysteine enemas and pancreatic 
replacement enzymes given orally and by enema. The pathogenesis of this 
disorder and the basis for the treatment are described. Recognition of 
this complication and familiarity with its medical management are important in 
caring for the older child with cystic fibrosis. 