Pulmonary involvement in adults with cystic fibrosis.

Cystic fibrosis is no longer rare in adults. The lung is the 
main target organ and the basic lesion is bronchial obstruction leading 
to bronchiectasis. Interstitial infiltrates and cyst-like changes are characteristic on roentgenography. 
Complications include pulmonary hypertension, pneumonitis, hemorrhage, and pneumothorax. Little correlation exists 
between respiratory tract and pancreatic and gastrointestinal involvement, despite similarities in 
pathogenesis. Pulmonary cystic fibrosis in adults does not always resemble the 
condition in children, and must be differentiated from other chronic interstitial 
diseases. 