Whole cell heat-killed gram-negative bacilli vaccine.

This preliminary clinical study is of the ability of a multivalent heat-killed 
whole cell gram-negative bacilli vaccine to be tolerated and to evoke 
an antibody response in groups of patients who have a manifest 
need for increased resistance to gram-negative bacilli. Three groups of patients 
were studied: 35 burn patients; seven small children with cystic fibrosis; 
and 35 patients who were about to undergo coronary vein grafts. 
The results of vaccination were different in each of the three 
groups of patients that were vaccinated. 