The electron microscopic appearance of presecreted gastric mucus in cystic fibrosis.

Gastric mucosal biopsies from eight new untreated patients with cystic fibrosis (CF) 
and two normal subjects were studied by quantitative techniques of electron 
microscopy (EM) to determine whether presecreted gastric mucus was more compact 
(viscid) than normal. Analysis of variance techniques show no differences between 
means of all groups studied. These observations suggest that mucus may 
not be viscid prior to secretion. Electron microscopy of gastric mucus 
does not appear to be of diagnostic value in CF. 