Glycosidases in serum of cystic fibrosis patients.

In a study of eight glycosidases in serum samples from 72 cystic 
fibrosis patients, 85 cystic fibrosis parents and 34 healthy and diseased 
controls, significant elevations of mean alpha-glucosidase levels were found in cystic 
fibrosis patients. All other glycosidases did not show any significant change. 
Mean alpha-glucosidase levels in obligate heterozygotes were the same as in 
control individuals. Moreover, alpha-glucosidase levels in cystic fibrosis patients correlated with 
the degree of clinical impairment as measured by the Schwachman score. 
