Letter: Skin wrinkling in cystic fibrosis.

Dr. Economou-Mavrou and his colleagues appear to have misunderstood my previous note 
concerning skin wrinkling in cystic fibrosis. The range of normality varies 
in different climatic conditions, and in Aukland wrinkling does not appear 
in cool tap-water (18-22 C) under 3 minutes in normals. Skin 
wrinkling on immersion appears to be age-related, but is difficult to 
detect reliably in the newborn. Prior washing of the hands, or 
immersion in sea-water (even the day before), accelerates skin wrinkling, as 
does warm weather. I would suggest that "normality" needs redefining in 
Athens if 6 of 17 "normals" were "abnormal". 